SUMMARY of alleged image manipulation

Article No.1  → J Biol Chem. 2010 May 7;285(19):14747-55.
Article No.2  → Cell. 2008 May 16;133(4):627-39.
Article No.3  → Mol Cell Biol. 2006 Nov;26(21):7966-76.
Article No.4   → EMBO J. 2006 Mar 8;25(5):1081-92.
Article No.5  → EMBO J. 2004 Dec 8;23(24):4813-23.
Article No.6  → EMBO J. 2004 Apr 7;23(7):1598-608.

See also  → Alleged image fraud at the University of Tokyo 
See also  → Alleged image fraud at MD Anderson Cancer Center (Bharat Aggarwal lab)
See also  → Alleged image fraud (Michael Karin lab et al.)
See also  → Scientific misconduct at Tokyo Medical and Dental University (Akio Kawakami, MD)
ScienceInsider News   → Whistleblower Uses YouTube to Assert Claims of Scientific Misconduct

Cell. 2008 May 16;133(4):627-39.

Epigenetic control of rDNA loci in response to intracellular energy status.

Murayama A, Ohmori K, Fujimura A, Minami H, Yasuzawa-Tanaka K, Kuroda T, Oie S, Daitoku H, Okuwaki M, Nagata K, Fukamizu A, Kimura K, Shimizu T, Yanagisawa J.

Source

Graduate School of Life and Environmental Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8572, Japan.

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Fig.2E　

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Fig.3D　

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EMBO J. 2004 Dec 8;23(24):4813-23. Epub 2004 Nov 11.

Ligand-dependent switching of ubiquitin-proteasome pathways for estrogen receptor.

Tateishi Y, Kawabe Y, Chiba T, Murata S, Ichikawa K, Murayama A, Tanaka K, Baba T, Kato S, Yanagisawa J.

Source

Graduate School of Life and Environmental Sciences, University of Tsukuba, Tsukuba Science City, Ibaraki, Japan.

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Two lanes of Control IgG in Fig.1B  in EMBO J (2004 Dec 8;23(24):4813-23.) are similar to those in Fig.1B in Mol Cell Biol ( 2006 Nov;26(21):7966-76. ).

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GAPDH lanes of bottom-most panel in Fig.1C in EMBO J (2004 Dec 8;23(24):4813-23.)

are identical to GAPDH lanes in Fig.6A ERα(ΔAD) in Mol Cell Biol (2006 Nov;26(21):7966-76.)  

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In the top panel (alpha-CHIP) in Fig. 2C, there is discontinuity along a straight line separating 1st  lane (WCE) and 2nd lane (-). 

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GAPDH lanes of bottom-most panel in  Fig. 4A in EMBO J (2004 Dec 8;23(24):4813-23.) are similar to GAPDH lanes of 2nd panel from the top in  Fig. 1E in Mol Cell Biol.  (2006 Nov;26(21):7966-76.).

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J Biol Chem. 2010 May 7;285(19):14747-55. Epub 2010 Mar 5.

Estrogen inhibits transforming growth factor beta signaling by promoting Smad2/3 degradation.

Ito I, Hanyu A, Wayama M, Goto N, Katsuno Y, Kawasaki S, Nakajima Y, Kajiro M, Komatsu Y, Fujimura A, Hirota R, Murayama A, Kimura K, Imamura T,Yanagisawa J.

Source

Graduate School of Life and Environmental Sciences, University of Tsukuba, Tsukuba Science City, Ibaraki 305-8572, Japan.

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In the top panel ( I.B.:alpha-myc (Smad2)) in Fig. 4C, the 4th lane from the left is similar to the right-most lane.　

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Beta-actin lanes in the bottom panel in Fig.3B are the same as 2nd to 7th lanes from the left in Smad2 panel in Fig.4C.

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EMBO J. 2006 Mar 8;25(5):1081-92. Epub 2006 Feb 23.

A specific CpG site demethylation in the human interleukin 2 gene promoter is an epigenetic memory.

Murayama A, Sakura K, Nakama M, Yasuzawa-Tanaka K, Fujita E, Tateishi Y, Wang Y, Ushijima T, Baba T, Shibuya K, Shibuya A, Kawabe Y,Yanagisawa J.

Source

Graduate School of Life and Environmental Sciences, University of Tsukuba, Tsukuba Science City, Ibaraki, Japan.

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Fig.3  b-actin

http://www.nature.com/emboj/journal/v25/n5/fig_tab/7601012a_F3.html

Fig.4　input

http://www.nature.com/emboj/journal/v25/n5/fig_tab/7601012a_F4.html

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